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QCR9 ubiquinol--cytochrome-c reductase subunit 9 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853095, updated on 13-Apr-2024

Summary

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Gene symbol
QCR9
Gene description
ubiquinol--cytochrome-c reductase subunit 9
Primary source
SGD:S000003415
Locus tag
YGR183C
See related
AllianceGenome:SGD:S000003415
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
UCR9
Summary
Contributes to ubiquinol-cytochrome-c reductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III assembly. Located in mitochondrion. Part of mitochondrial respiratory chain complex III. Orthologous to human UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: VII
Exon count:
2
Sequence:
Chromosome: VII; NC_001139.9 (859063..859476, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene protein translocase subunit TIM13 Neighboring gene E3 ubiquitin-protein ligase UBR1 Neighboring gene tyrosine--tRNA ligase TYS1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Subunit 9 of the Saccharomyces cerevisiae cytochrome bc1 complex is required for insertion of EPR-detectable iron-sulfur cluster into the Rieske iron-sulfur protein. Phillips JD, et al. J Biol Chem, 1993 Jun 5. PMID 8389362
  2. Isolation and characterization of QCR9, a nuclear gene encoding the 7.3-kDa subunit 9 of the Saccharomyces cerevisiae ubiquinol-cytochrome c oxidoreductase complex. An intron-containing gene with a conserved sequence occurring in the intron of COX4. Phillips JD, et al. J Biol Chem, 1990 Dec 5. PMID 2174427
  3. Deletion of subunit 9 of the Saccharomyces cerevisiae cytochrome bc1 complex specifically impairs electron transfer at the ubiquinol oxidase site (center P) in the bc1 complex. Graham LA, et al. FEBS Lett, 1992 Nov 30. PMID 1332881
  4. A pathogenic cytochrome b mutation reveals new interactions between subunits of the mitochondrial bc1 complex. Saint-Georges Y, et al. J Biol Chem, 2002 Dec 20. PMID 12384503
  5. Enhanced hexose fermentation by Saccharomyces cerevisiae through integration of stoichiometric modeling and genetic screening. Quarterman J, et al. J Biotechnol, 2015 Jan 20. PMID 25435378

See all (73) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial respiratory chain complex III assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex III IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial respiratory chain complex III IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial respiratory chain complex III IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in respirasome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquinol--cytochrome-c reductase subunit 9
NP_011699.1
  • Subunit 9 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    859063..859476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181312.1 → NP_011699.1  TPA: ubiquinol--cytochrome-c reductase subunit 9 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011699.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUW6, P22289
    UniProtKB/TrEMBL
    A6ZUJ4, C8Z977, G2WER2
    Conserved Domains (1) summary
    pfam05365
    Location:4 → 56
    UCR_UQCRX_QCR9; Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6HU9_I.1
6HU9_T.1
6T0B_I.1
6T0B_T.1
6T15_I.1
6T15_T.1
P22289.2

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