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YUR1 mannosyltransferase YUR1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853302, updated on 11-Apr-2024

Summary

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Gene symbol
YUR1
Gene description
mannosyltransferase YUR1
Primary source
SGD:S000003675
Locus tag
YJL139C
See related
AllianceGenome:SGD:S000003675
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables mannosyltransferase activity. Involved in cell wall mannoprotein biosynthetic process and protein N-linked glycosylation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (151713..152999, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Irc9p Neighboring gene serine/threonine protein kinase YAK1 Neighboring gene DNA-directed RNA polymerase II subunit RPB4 Neighboring gene translation initiation factor eIF4A Neighboring gene glycogenin glucosyltransferase GLG2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Adaptive evolution of nontransitive fitness in yeast. Buskirk SW, et al. Elife, 2020 Dec 29. PMID 33372653, Free PMC Article
  2. Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Hill K, et al. Genetics, 1992 Feb. PMID 1541391, Free PMC Article
  3. Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. Lussier M, et al. J Biol Chem, 1996 May 3. PMID 8631921
  4. Biosynthesis of the side chain of yeast glycosylphosphatidylinositol anchors is operated by novel mannosyltransferases located in the endoplasmic reticulum and the Golgi apparatus. Sipos G, et al. J Biol Chem, 1995 Aug 25. PMID 7649981
  5. Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI. Katsoulou C, et al. Yeast, 1996 Jun 30. PMID 8813765

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables alpha-1,2-mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables mannosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell wall mannoprotein biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell wall mannoprotein biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mannosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mannosyltransferase YUR1
NP_012396.1
  • Mannosyltransferase involved in protein N-glycosylation; member of the KTR1 family; located in the Golgi apparatus; YUR1 has a paralog, KTR2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    151713..152999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181572.1 → NP_012396.1  TPA: mannosyltransferase YUR1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012396.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW45, P26725
    UniProtKB/TrEMBL
    A0A7I9F6F8, A6ZQJ0, B3LPX9, B5VL40, C8ZB78, G2WGN1, N1P1H5
    Conserved Domains (1) summary
    COG5020
    Location:7 → 424
    KTR1; Mannosyltransferase [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26725.1

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