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MPH3 alpha-glucoside permease [ Saccharomyces cerevisiae S288C ]

Gene ID: 853625, updated on 11-Apr-2024

Summary

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Gene symbol
MPH3
Gene description
alpha-glucoside permease
Primary source
SGD:S000003921
Locus tag
YJR160C
See related
AllianceGenome:SGD:S000003921
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable carbohydrate:proton symporter activity and maltose transmembrane transporter activity. Involved in carbohydrate transport. Located in cell periphery and fungal-type vacuole. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (738008..739816, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene hexose transporter HXT16 Neighboring gene L-iditol 2-dehydrogenase SOR1 Neighboring gene Cos5p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the putative maltose transporters encoded by YDL247w and YJR160c. Day RE, et al. Yeast, 2002 Sep 15. PMID 12210897
  2. Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Brown CA, et al. Curr Biol, 2010 May 25. PMID 20471265, Free PMC Article
  3. A Novel Sterol-Signaling Pathway Governs Azole Antifungal Drug Resistance and Hypoxic Gene Repression in Saccharomyces cerevisiae. Serratore ND, et al. Genetics, 2018 Mar. PMID 29263028, Free PMC Article
  4. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article
  5. Exploring the yeast acetylome using functional genomics. Kaluarachchi Duffy S, et al. Cell, 2012 May 11. PMID 22579291, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables maltose transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in maltose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in maltose transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in fungal-type vacuole HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alpha-glucoside permease
NP_012694.1
  • Alpha-glucoside permease; transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    738008..739816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181818.1 → NP_012694.1  TPA: alpha-glucoside permease [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012694.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B5VF36, D6VWX8, P0CE00
    UniProtKB/TrEMBL
    N1P3Z4
    Conserved Domains (1) summary
    TIGR00879
    Location:72 → 556
    SP; MFS transporter, sugar porter (SP) family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CE00.1

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