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GPM3 phosphoglycerate mutase family protein GPM3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854098, updated on 13-Apr-2024

Summary

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Gene symbol
GPM3
Gene description
phosphoglycerate mutase family protein GPM3
Primary source
SGD:S000005417
Locus tag
YOL056W
See related
AllianceGenome:SGD:S000005417
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable phosphoglycerate mutase activity. Predicted to be involved in glycolytic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in familial erythrocytosis 8. Orthologous to human BPGM (bisphosphoglycerate mutase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (223268..224179)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene argininosuccinate synthase Neighboring gene dipeptidyl-peptidase III Neighboring gene trifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase/thiaminase Neighboring gene tRNA-Gly

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Time-dependent regulation analysis dissects shifts between metabolic and gene-expression regulation during nitrogen starvation in baker's yeast. van Eunen K, et al. FEBS J, 2009 Oct. PMID 19691496
  2. Parallel analysis of genetic selections using whole genome oligonucleotide arrays. Cho RJ, et al. Proc Natl Acad Sci U S A, 1998 Mar 31. PMID 9520439, Free PMC Article
  3. Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. Piya G, et al. PLoS One, 2015. PMID 25719602, Free PMC Article
  4. Investigation of two yeast genes encoding putative isoenzymes of phosphoglycerate mutase. Heinisch JJ, et al. Yeast, 1998 Feb. PMID 9544241
  5. Exposing the fitness contribution of duplicated genes. DeLuna A, et al. Nat Genet, 2008 May. PMID 18408719

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
  
enables intramolecular phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables phosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 

General protein information

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Preferred Names
phosphoglycerate mutase family protein GPM3
NP_014585.1
  • Nonfunctional homolog of Gpm1p phosphoglycerate mutase; if functional, would convert 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; GPM3 has a paralog, GPM2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    223268..224179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183311.1 → NP_014585.1  TPA: phosphoglycerate mutase family protein GPM3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014585.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W211, Q12326
    UniProtKB/TrEMBL
    A0A6A5Q3M4, A6ZNF4, B3LJ03, B5VRJ5, C7GK23, C8ZHQ7, G2WMH8, N1NY26
    Conserved Domains (1) summary
    COG0588
    Location:6 → 284
    GpmA; Phosphoglycerate mutase (BPG-dependent) [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12326.1

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