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COX3 cytochrome c oxidase subunit 3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854627, updated on 13-Apr-2024

Summary

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Gene symbol
COX3
Gene description
cytochrome c oxidase subunit 3
Primary source
SGD:S000007283
Locus tag
Q0275
See related
AllianceGenome:SGD:S000007283
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288C (strain: S288C, substrain: FY1679)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
OXI2
Summary
Contributes to cytochrome-c oxidase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of mitochondrial respiratory chain complex IV. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Sequence:
Chromosome: MT; NC_001224.1 (79213..80022)

Chromosome MT - NC_001224.1Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene tRNA-Val Neighboring gene tRNA-Met Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001224.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recombinational analysis of oxi2 mutants and preliminary analysis of their translation products in S. cerevisiae. Baranowska H, et al. Curr Genet, 1983 Jun. PMID 24173282
  2. Expression of green fluorescent protein from a recoded gene inserted into Saccharomyces cerevisiae mitochondrial DNA. Cohen JS, et al. Mitochondrion, 2001 Aug. PMID 16120277
  3. Assembly of the mitochondrial membrane system. Characterization of the oxi2 transcript and localization of its promoter in Saccharomyces cerevisiae D273-10B. Thalenfeld BE, et al. J Biol Chem, 1983 Jan 10. PMID 6294116
  4. mit-Mutations in the structural gene of subunit III of cytochrome oxidase in Saccharomyces cerevisiae. Stephenson G, et al. Biochim Biophys Acta, 1981 May 29. PMID 6264959
  5. Interaction of integral and peripheral membrane proteins: affinity labeling of yeast cytochrome oxidase by modified yeast cytochrome c. Birchmeier W, et al. Proc Natl Acad Sci U S A, 1976 Dec. PMID 188034, Free PMC Article

See all (95) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to cytochrome-c oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cytochrome-c oxidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in aerobic electron transport chain IEA
Inferred from Electronic Annotation
more info
  
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial electron transport, cytochrome c to oxygen IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex IV IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome c oxidase subunit 3
NP_009328.1
  • Subunit III of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001224.1 Reference assembly

    Range
    79213..80022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_009328.1 cytochrome c oxidase subunit 3 (mitochondrion) [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009328.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    A0A0A7P087, P00420, Q9ZZV9
    UniProtKB/TrEMBL
    A0A0G3F1J2, A0A343UW85, A7LCP4
    Conserved Domains (1) summary
    pfam00510
    Location:12 → 269
    COX3; Cytochrome c oxidase subunit III
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6HU9_c.1
6HU9_o.1
6T0B_c.1
6T0B_p.1
6T15_c.1
P00420.3

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