IMA3 oligo-1,6-glucosidase IMA3 [Saccharomyces cerevisiae S288C] - Gene

Summary

Gene symbol: IMA3
Gene description: oligo-1,6-glucosidase IMA3
Primary source: SGD:S000001434
Locus tag: YIL172C
See related: AllianceGenome:SGD:S000001434
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables oligo-1,6-glucosidase activity and sucrose alpha-glucosidase activity. Involved in disaccharide catabolic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to several human genes including SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome IX - NC_001141.2 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables alpha-amylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables glucan 1,4-alpha-maltotriohydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables maltose alpha-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oligo-1,6-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oligo-1,6-glucosidase activity	IDA Inferred from Direct Assay more info	PubMed
enables oligo-1,6-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables oligo-1,6-glucosidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables sucrose alpha-glucosidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sucrose alpha-glucosidase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in disaccharide catabolic process	IEA Inferred from Electronic Annotation more info
involved_in disaccharide catabolic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in maltose catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in maltose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sucrose catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_012096.1

Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima3p overexpression allows the ima1 null mutant to grow on isomaltose; lower activitiy and thermostability in vitro than Ima2p despite sequence difference of only 3 amino acids; cleaves alpha-1,3 linkage of nigerose and turanose, but not alpha-1,5 of leucrose; identical to IMA4

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain