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VBA1 Vba1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855113, updated on 17-May-2024

Summary

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Gene symbol
VBA1
Gene description
Vba1p
Primary source
FungiDB:YMR088C
Locus tag
YMR088C
See related
SGD:S000004694; AllianceGenome:SGD:S000004694
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables basic amino acid transmembrane transporter activity. Involved in basic amino acid transport. Located in fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (443414..445102, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Seg1p Neighboring gene putative ADP-ribose 1''-phosphate phosphatase Neighboring gene m-AAA protease subunit YTA12 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vba4p, a vacuolar membrane protein, is involved in the drug resistance and vacuolar morphology of Saccharomyces cerevisiae. Kawano-Kawada M, et al. Biosci Biotechnol Biochem, 2016. PMID 26325352
  2. A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. Shimazu M, et al. J Biol Chem, 2005 Feb 11. PMID 15572352
  3. A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Kucejova B, et al. Genetics, 2005 Oct. PMID 16020778, Free PMC Article
  4. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Fromont-Racine M, et al. Nat Genet, 1997 Jul. PMID 9207794
  5. Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis. Nsamba ET, et al. J Cell Biol, 2021 Dec 6. PMID 34739032, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables basic amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables basic amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables basic amino acid transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in basic amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in basic amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in basic amino acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in fungal-type vacuole membrane HDA PubMed 
is_active_in fungal-type vacuole membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Vba1p
NP_013806.1
  • Permease of basic amino acids in vacuolar membrane; targeted to vacuole via AP-3 pathway

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    443414..445102 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182588.1 → NP_013806.1  TPA: Vba1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013806.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZR1, Q04301
    UniProtKB/TrEMBL
    A0A8H4BXD3, A6ZME5, B3LLX9, B5VPL4, C7GL38, C8ZEU1, G2WKD6
    Conserved Domains (1) summary
    cd17502
    Location:42 → 469
    MFS_Azr1_MDR_like; Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04301.1

Gene LinkOut

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