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COX7 cytochrome c oxidase subunit VII [ Saccharomyces cerevisiae S288C ]

Gene ID: 855298, updated on 17-May-2024

Summary

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Gene symbol
COX7
Gene description
cytochrome c oxidase subunit VII
Primary source
FungiDB:YMR256C
Locus tag
YMR256C
See related
SGD:S000004869; AllianceGenome:SGD:S000004869
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Contributes to cytochrome-c oxidase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of mitochondrial respiratory chain complex IV. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (778945..779127, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gfd1p Neighboring gene Pet111p Neighboring gene Roy1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yeast cytochrome c oxidase subunit VII is essential for assembly of an active enzyme. Cloning, sequencing, and characterization of the nuclear-encoded gene. Aggeler R, et al. J Biol Chem, 1990 Sep 25. PMID 2168889
  2. Nucleotide sequence of the gene encoding cytochrome c oxidase subunit VII from Saccharomyces cerevisiae. Calder KM, et al. Nucleic Acids Res, 1990 Mar 25. PMID 2158084, Free PMC Article
  3. Monitoring yeast mitochondria with peroxiredoxin-based redox probes: the influence of oxygen and glucose availability. Pastor-Flores D, et al. Interface Focus, 2017 Apr 6. PMID 28382205, Free PMC Article
  4. Study of a region on yeast chromosome XIII that complements pet G199 mutants (COX7) and carries a new non-essential gene. Nobrega MP, et al. Braz J Med Biol Res, 1998 Mar. PMID 9698782
  5. Deletion of the COX7 gene in Saccharomyces cerevisiae reveals a role for cytochrome c oxidase subunit VII in assembly of remaining subunits. Calder KM, et al. Mol Microbiol, 1991 Jul. PMID 1658541

See all (67) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
Inferred from Electronic Annotation
more info
  
involved_in oxidative phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex IV IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial respiratory chain complex IV IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome c oxidase subunit VII
NP_013983.1
  • Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    778945..779127 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182763.1 → NP_013983.1  TPA: cytochrome c oxidase subunit VII [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013983.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W082, P10174
    UniProtKB/TrEMBL
    A0A6A5PQU1, A6ZMX1, B3LME4, C7GR96, C8ZFC2, G2WKW4, N1NZ38
    Conserved Domains (1) summary
    pfam02238
    Location:3 → 54
    COX7a; Cytochrome c oxidase subunit VII
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P10174.3

Gene LinkOut

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