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SOL1 Sol1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855769, updated on 3-Dec-2023

Summary

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Gene symbol
SOL1
Gene description
Sol1p
Primary source
SGD:S000005317
Locus tag
YNR034W
See related
AllianceGenome:SGD:S000005317
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable 6-phosphogluconolactonase activity. Involved in tRNA export from nucleus. Located in nucleus. Orthologous to human PGLS (6-phosphogluconolactonase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (690321..691286)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene ubiquitin-like protein HUB1 Neighboring gene 4-amino-4-deoxychorismate synthase Neighboring gene Ego4p Neighboring gene Arc35p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family. Shen WC, et al. Genetics, 1996 Jun. PMID 8725220, Free PMC Article
  2. Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism. Stanford DR, et al. Genetics, 2004 Sep. PMID 15454531, Free PMC Article
  3. The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Musso G, et al. Genome Res, 2008 Jul. PMID 18463300, Free PMC Article
  4. Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Pinsky BA, et al. Mol Cell Biol, 2006 Apr. PMID 16537909, Free PMC Article
  5. Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast. Jin L, et al. Mol Cell Biol, 2015 Oct. PMID 26217015, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 6-phosphogluconolactonase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 6-phosphogluconolactonase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pentose-phosphate shunt IEA
Inferred from Electronic Annotation
more info
  
involved_in pentose-phosphate shunt, oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA export from nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sol1p
NP_014432.3
  • Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL1 has a paralog, SOL2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    690321..691286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183211.3 → NP_014432.3  TPA: Sol1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014432.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1K9, P50278
    UniProtKB/TrEMBL
    A0A6A5Q5P3, A6ZSA8, B3LPK9, B5VR63, C7GLM3, C8ZFR2, G2WL91, N1P4S8
    Conserved Domains (1) summary
    cd01400
    Location:92 → 296
    6PGL; 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50278.1

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