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BIO5 Bio5p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855793, updated on 13-Apr-2024

Summary

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Gene symbol
BIO5
Gene description
Bio5p
Primary source
SGD:S000005339
Locus tag
YNR056C
See related
AllianceGenome:SGD:S000005339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables transmembrane transporter activity. Involved in biotin biosynthetic process and vitamin transport. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (731618..733303, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene Hol1p Neighboring gene dethiobiotin synthase Neighboring gene adenosylmethionine-8-amino-7-oxononanoate transaminase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vhr1p, a new transcription factor from budding yeast, regulates biotin-dependent expression of VHT1 and BIO5. Weider M, et al. J Biol Chem, 2006 May 12. PMID 16533810
  2. Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Phalip V, et al. Gene, 1999 May 17. PMID 10333520
  3. Identification by comparative transcriptomics of core regulatory genes for higher alcohol production in a top-fermenting yeast at different temperatures in beer fermentation. Sun ZG, et al. Appl Microbiol Biotechnol, 2019 Jun. PMID 31073877
  4. Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Mattiazzi Ušaj M, et al. Metallomics, 2015 Sep. PMID 26067383
  5. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Aguilar PS, et al. Nat Struct Mol Biol, 2010 Jul. PMID 20526336, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The presented data characterize Vhr1p as an essential component of the biotin-dependent signal transduction cascade in yeast.
    Title: Vhr1p, a new transcription factor from budding yeast, regulates biotin-dependent expression of VHT1 and BIO5.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biotin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vitamin transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in vitamin transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Bio5p
NP_014454.3
  • Putative transmembrane protein involved in the biotin biosynthesis; responsible for uptake of 7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    731618..733303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183233.3 → NP_014454.3  TPA: Bio5p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014454.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1N1, P53744
    UniProtKB/TrEMBL
    A0A8H4BW79, A6ZSD0, B5VR81, N1NXU5
    Conserved Domains (1) summary
    TIGR00907
    Location:38 → 555
    2A0304; amino acid permease (GABA permease)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53744.1

Gene LinkOut

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