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VMA11 H(+)-transporting V0 sector ATPase subunit c' [ Saccharomyces cerevisiae S288C ]

Gene ID: 855842, updated on 13-Apr-2024

Summary

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Gene symbol
VMA11
Gene description
H(+)-transporting V0 sector ATPase subunit c'
Primary source
SGD:S000006155
Locus tag
YPL234C
See related
AllianceGenome:SGD:S000006155
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CLS9; TFP3
Summary
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in vacuolar acidification. Located in fungal-type vacuole. Is integral component of membrane. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (104946..105440, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene putative serine/threonine protein kinase ENV7 Neighboring gene RuvB family ATP-dependent DNA helicase reptin Neighboring gene MIND complex subunit NSL1 Neighboring gene syntaxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables proton-transporting ATPase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
enables proton-transporting ATPase activity, rotational mechanism TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vacuolar acidification TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in fungal-type vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
part_of vacuolar proton-transporting V-type ATPase, V0 domain TAS
Traceable Author Statement
more info
 PubMed 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
H(+)-transporting V0 sector ATPase subunit c'
NP_015090.1
  • Vacuolar ATPase V0 domain subunit c'; involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    104946..105440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184048.1 → NP_015090.1  TPA: H(+)-transporting V0 sector ATPase subunit c' [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015090.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3D6, P32365, P32842
    UniProtKB/TrEMBL
    A0A6A5Q2E5, A6ZW21, B3LKJ7, B5VSU8, C7GU73, C8ZIE5, G2WNV1, N1NW63
    Conserved Domains (2) summary
    cd18176
    Location:92 → 159
    ATP-synt_Vo_c_ATP6C_rpt2; V-type proton ATPase 16 kDa proteolipid subunit (ATP6C/ATP6V0C/ATP6L/ATPL) and similar proteins
    cl00466
    Location:17 → 124
    ATP-synt_C; ATP synthase subunit C
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
5VOX_S.1
5VOY_S.1
5VOZ_S.1
6C6L_D.1
6O7V_o.1
6O7W_o.1
6O7X_o.1
6PE4_H.1
6PE5_H.1
P32842.1

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