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KTR6 putative mannosyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 856054, updated on 11-Apr-2024

Summary

Gene symbol
KTR6
Gene description
putative mannosyltransferase
Primary source
SGD:S000005974
Locus tag
YPL053C
See related
AllianceGenome:SGD:S000005974
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MNN6
Summary
Enables mannosylphosphate transferase activity. Involved in fungal-type cell wall organization and protein N-linked glycosylation. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endoplasmic reticulum and membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (457118..458458, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Lge1p Neighboring gene Lee1p Neighboring gene Oaz1p Neighboring gene Arf family GTPase ARL3

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables alpha-1,2-mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannosylphosphate transferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell wall mannoprotein biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fungal-type cell wall organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mannosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein N-linked glycosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in fungal-type vacuole HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative mannosyltransferase
NP_015272.1
  • Probable mannosylphosphate transferase; involved in the synthesis of core oligosaccharides in protein glycosylation pathway; facilitates the exit of Mnn4p from the ER via COPII-coated vesicles; member of the KRE2/MNT1 mannosyltransferase family; KTR6 has a paralog, KRE2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    457118..458458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183867.1NP_015272.1  TPA: putative mannosyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015272.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3W1, P54070
    UniProtKB/TrEMBL
    A0A8H4BUU5, A6ZWJ5, B3LL14, C7GU02, C8ZIX7, G2WPC5
    Conserved Domains (1) summary
    COG5020
    Location:7443
    KTR1; Mannosyltransferase [Carbohydrate transport and metabolism]