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QCR10 ubiquinol--cytochrome-c reductase subunit 10 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856390, updated on 13-Apr-2024

Summary

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Gene symbol
QCR10
Gene description
ubiquinol--cytochrome-c reductase subunit 10
Primary source
SGD:S000003529
Locus tag
YHR001W-A
See related
AllianceGenome:SGD:S000003529
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Contributes to ubiquinol-cytochrome-c reductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Part of mitochondrial respiratory chain complex III. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: VIII
Exon count:
2
Sequence:
Chromosome: VIII; NC_001140.6 (107826..108122)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L14B Neighboring gene oxysterol-binding protein related protein OSH7 Neighboring gene coenzyme A transporter Neighboring gene tRNA threonylcarbamoyladenosine dehydratase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The respiratory chain in yeast behaves as a single functional unit. Boumans H, et al. J Biol Chem, 1998 Feb 27. PMID 9478928
  2. Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex. Brandt U, et al. J Biol Chem, 1994 Apr 29. PMID 8175712
  3. Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane. Zara V, et al. FEBS J, 2009 Apr. PMID 19236481, Free PMC Article
  4. Whole-Genome Approach to Understanding the Mechanism of Action of a Histatin 5-Derived Peptide. Bullock CB, et al. Antimicrob Agents Chemother, 2020 Feb 21. PMID 31843998, Free PMC Article
  5. Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b. Zara V, et al. Eur J Biochem, 2004 Mar. PMID 15009199

See all (64) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in aerobic respiration IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex III IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial respiratory chain complex III IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial respiratory chain complex III IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in respirasome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquinol--cytochrome-c reductase subunit 10
NP_011864.1
  • Subunit of the ubiqunol-cytochrome c oxidoreductase complex; this complex comprises part of the mitochondrial respiratory chain; members include Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    107826..108122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181426.1 → NP_011864.1  TPA: ubiquinol--cytochrome-c reductase subunit 10 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011864.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKR8, O13538, P37299, Q9T2W2
    UniProtKB/TrEMBL
    A6ZSQ3, B3LSB9, C8ZA67, G2WF67, N1P352
    Conserved Domains (1) summary
    pfam09796
    Location:15 → 76
    QCR10; Ubiquinol-cytochrome-c reductase complex subunit (QCR10)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6HU9_J.1
6HU9_U.1
6T0B_J.1
6T0B_U.1
6T15_J.1
6T15_U.1
P37299.2

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