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nadD nicotinate-nucleotide adenylyltransferase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885457, updated on 6-Oct-2023

Summary

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Gene symbol
nadD
Gene description
nicotinate-nucleotide adenylyltransferase
Locus tag
Rv2421c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2718173..2718808, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene DegV domain-containing protein Neighboring gene hypothetical protein Neighboring gene glucosyl-3-phosphoglycerate phosphatase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery. Rodionova IA, et al. J Biol Chem, 2015 Mar 20. PMID 25631047, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. detailed steady-state kinetic analysis of MtNadD suggests that ATP must first bind to allow efficient NaMN binding and catalysis
    Title: Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
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Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
nicotinate-nucleotide adenylyltransferase
NP_216937.1
  • deamido-NAD(+) pyrophosphorylase (deamido-NAD(+) diphosphorylase) (nicotinate mononucleotide adenylyltransferase) (NAMN adenylyltransferase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2718173..2718808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216937.1 nicotinate-nucleotide adenylyltransferase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216937.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M4D9
    Conserved Domains (1) summary
    PRK00071
    Location:1 → 191
    nadD; nicotinate-nucleotide adenylyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WJJ5.1

Gene LinkOut

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Molecular Biology Databases