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mbtB phenyloxazoline synthase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885838, updated on 4-Apr-2024

Summary

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Gene symbol
mbtB
Gene description
phenyloxazoline synthase
Locus tag
Rv2383c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2671593..2675837, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene peptide synthetase Neighboring gene peptide synthetase Neighboring gene polyketide synthetase Neighboring gene polyketide synthetase Neighboring gene 2,3-dihydroxybenzoate-AMP ligase Neighboring gene acetyl hydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosis. McMahon MD, et al. J Bacteriol, 2012 Jun. PMID 22447909, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The A domain of MbtB preferentially activates l-threonine.
    Title: Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
phenyloxazoline synthase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2671593..2675837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216899.1 phenyloxazoline synthase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216899.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0Y1CPJ7
    Conserved Domains (5) summary
    COG3208
    Location:1183 → 1413
    GrsT; Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and catabolism]
    COG3433
    Location:9 → 77
    DhbB2; Aryl carrier domain [Secondary metabolites biosynthesis, transport and catabolism]
    cd12114
    Location:566 → 1037
    A_NRPS_TlmIV_like; The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes
    cd19535
    Location:99 → 520
    Cyc_NRPS; Cyc (heterocyclization) domain of nonribosomal peptide synthetases (NRPSs); belongs to the Condensation-domain family
    pfam00550
    Location:1064 → 1126
    PP-binding; Phosphopantetheine attachment site
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WQ63.1

Gene LinkOut

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Molecular Biology Databases