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fadB2 3-hydroxybutyryl-CoA dehydrogenase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886288, updated on 6-Oct-2023

Summary

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Gene symbol
fadB2
Gene description
3-hydroxybutyryl-CoA dehydrogenase
Locus tag
Rv0468
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (558895..559755)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene isocitrate lyase Neighboring gene mycolic acid synthase UmaA Neighboring gene cyclopropane mycolic acid synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation. Cox JAG, et al. Acta Crystallogr D Struct Biol, 2019 Jan 1. PMID 30644849, Free PMC Article
  2. Characterization of a beta-hydroxybutyryl-CoA dehydrogenase from Mycobacterium tuberculosis. Taylor RC, et al. Microbiology (Reading), 2010 Jul. PMID 20378648
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the crystal structure of this enzyme in a ligand-free form is reported at 2.1 A resolution. FadB2 crystallized as a dimer with three unique dimer copies per asymmetric unit.
    Title: Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation.
  2. FadB2 functions as a fatty acyl dehydrogenase involved in the beta-oxidation of fatty acids.
    Title: Characterization of a beta-hydroxybutyryl-CoA dehydrogenase from Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
3-hydroxybutyryl-CoA dehydrogenase
NP_214982.1
  • beta-hydroxybutyryl-CoA dehydrogenase (BHBD)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    558895..559755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214982.1 3-hydroxybutyryl-CoA dehydrogenase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214982.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LZ32
    Conserved Domains (1) summary
    PRK07819
    Location:1 → 286
    PRK07819; 3-hydroxybutyryl-CoA dehydrogenase; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WNP7.1

Gene LinkOut

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Molecular Biology Databases