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proV glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886293, updated on 6-Oct-2023

Summary

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Gene symbol
proV
Gene description
glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV
Locus tag
Rv3758c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (4203287..4204417, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene prephenate dehydrogenase TyrA Neighboring gene hypothetical protein Neighboring gene glycine betaine/carnitine/choline/L-proline ABC transporter permease ProZ Neighboring gene glycine betaine/carnitine/choline/L-proline ABC transporter permease ProW Neighboring gene glycine betaine/carnitine/choline/L-proline ABC transporter substrate-binding lipoprotein ProX Neighboring gene membrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glycine betaine uptake by the ProXVWZ ABC transporter contributes to the ability of Mycobacterium tuberculosis to initiate growth in human macrophages. Price CT, et al. J Bacteriol, 2008 Jun. PMID 18390665, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. role of proXVWZ in allowing M. tuberculosis to obtain betaine from host macrophages and thereby contributes to early steps in colonizing this niche is reported
    Title: Glycine betaine uptake by the ProXVWZ ABC transporter contributes to the ability of Mycobacterium tuberculosis to initiate growth in human macrophages.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4203287..4204417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218275.1 glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218275.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A655I4C8
    Conserved Domains (1) summary
    COG1125
    Location:1 → 327
    OpuBA; ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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