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pyrE orotate phosphoribosyltransferase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886443, updated on 6-Oct-2023

Summary

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Gene symbol
pyrE
Gene description
orotate phosphoribosyltransferase
Locus tag
Rv0382c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
umpA
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Genomic context

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Sequence:
NC_000962.3 (457841..458380, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene RNA methyltransferase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene chaperone protein ClpB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis. Donini S, et al. Sci Rep, 2017 Apr 26. PMID 28446777, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
orotate phosphoribosyltransferase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    457841..458380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_177723.1 orotate phosphoribosyltransferase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for YP_177723.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7W3H3
    Conserved Domains (1) summary
    PRK00455
    Location:6 → 176
    pyrE; orotate phosphoribosyltransferase; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WHK9.1

Gene LinkOut

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Molecular Biology Databases
Research Materials