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ribH 6,7-dimethyl-8-ribityllumazine synthase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886681, updated on 27-Nov-2023

Summary

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Gene symbol
ribH
Gene description
6,7-dimethyl-8-ribityllumazine synthase
Locus tag
Rv1416
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (1591671..1592153)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene riboflavin synthase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene bifunctional riboflavin biosynthesis GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase Neighboring gene membrane protein Neighboring gene lipoprotein LprH Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors. Morgunova E, et al. Biochemistry, 2005 Mar 1. PMID 15723519
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. structure is a pentamer consisting of five subunits related by 5-fold local symmetry
    Title: Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
6,7-dimethyl-8-ribityllumazine synthase
NP_215932.2
  • RibH (6,7-dimethyl-8-ribityllumazine synthase) (DMRL synthase) (lumazine synthase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1591671..1592153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215932.2 6,7-dimethyl-8-ribityllumazine synthase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215932.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3M4R6, A0A679LDN9, A0A9P2H7N2, A5U2B8, R4MG60
    Conserved Domains (1) summary
    PRK00061
    Location:13 → 139
    ribH; 6,7-dimethyl-8-ribityllumazine synthase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WHE9.1

Gene LinkOut

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Molecular Biology Databases
Research Materials