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pks15 polyketide synthase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887291, updated on 4-Apr-2024

Summary

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Gene symbol
pks15
Gene description
polyketide synthase
Locus tag
Rv2947c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (3296350..3297840, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transposase Neighboring gene insertion sequence element IS1533 transposase Neighboring gene lipoprotein LppX Neighboring gene polyketide synthase Neighboring gene p-hydroxybenzoyl--AMP ligase Neighboring gene chorismate pyruvate-lyase Neighboring gene long-chain-fatty-acid--AMP ligase FadD29

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterisation of pks15/1 in clinical isolates of Mycobacterium tuberculosis from Mexico. Zenteno-Cuevas R, et al. Mem Inst Oswaldo Cruz, 2013 Sep. PMID 24037193, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results confirm the utility of locus pks15/1 as a molecular marker for identifying Asian lineages of the M. tuberculosis complex.
    Title: Characterisation of pks15/1 in clinical isolates of Mycobacterium tuberculosis from Mexico.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
polyketide synthase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3296350..3297840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217463.1 polyketide synthase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217463.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q50469
    Conserved Domains (2) summary
    cd00833
    Location:47 → 467
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam08990
    Location:17 → 42
    Docking; Erythronolide synthase docking
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P96284.2

Gene LinkOut

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