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serB2 phosphoserine phosphatase SerB [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 887815, updated on 6-Oct-2023

Summary

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Gene symbol
serB2
Gene description
phosphoserine phosphatase SerB
Locus tag
Rv3042c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (3401933..3403162, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene enoyl-CoA hydratase EchA17 Neighboring gene hypothetical protein Neighboring gene ABC transporter ATP-binding protein Neighboring gene cytochrome C oxidase cytochrome 1 Neighboring gene FeIII-dicitrate-binding periplasmic lipoprotein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulatory Mechanism of Mycobacterium tuberculosis Phosphoserine Phosphatase SerB2. Grant GA. Biochemistry, 2017 Dec 12. PMID 29140686
  2. High throughput screen identifies small molecule inhibitors specific for Mycobacterium tuberculosis phosphoserine phosphatase. Arora G, et al. J Biol Chem, 2014 Sep 5. PMID 25037224, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
phosphoserine phosphatase SerB
NP_217558.1
  • PSP (O-phosphoserine phosphohydrolase) (pspase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3401933..3403162 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217558.1 phosphoserine phosphatase SerB [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217558.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654TKF1
    Conserved Domains (3) summary
    cd04871
    Location:97 → 171
    ACT_PSP_2; ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB)
    COG3830
    Location:4 → 93
    ACT; ACT domain, binds amino acids and other small ligands [Signal transduction mechanisms]
    cd07500
    Location:181 → 360
    HAD_PSP; phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O53289.1

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