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bkdC branched-chain keto acid dehydrogenase E2 component [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888237, updated on 6-Oct-2023

Summary

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Gene symbol
bkdC
Gene description
branched-chain keto acid dehydrogenase E2 component
Locus tag
Rv2495c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2808758..2809939, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene antitoxin VapB38 Neighboring gene ribonuclease VapC38 Neighboring gene 3-methyl-2-oxobutanoate dehydrogenase subunit beta Neighboring gene 3-methyl-2-oxobutanoate dehydrogenase subunit alpha Neighboring gene citrate (pro-3S)-lyase subunit beta Neighboring gene oxidase regulatory-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  2. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  3. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
branched-chain keto acid dehydrogenase E2 component

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2808758..2809939 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217011.1 branched-chain keto acid dehydrogenase E2 component [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217011.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4MGC6
    Conserved Domains (4) summary
    cd06849
    Location:10 → 81
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PRK11856
    Location:7 → 392
    PRK11856; branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed
    pfam00198
    Location:181 → 391
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:119 → 153
    E3_binding; e3 binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O06159.2

Gene LinkOut

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Molecular Biology Databases
Research Materials