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aroB 3-dehydroquinate synthase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888392, updated on 6-Oct-2023

Summary

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Gene symbol
aroB
Gene description
3-dehydroquinate synthase
Locus tag
Rv2538c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (2861588..2862676, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene cytoplasmic peptidase PepQ Neighboring gene transmembrane protein Neighboring gene 3-dehydroquinate dehydratase Neighboring gene shikimate kinase Neighboring gene chorismate synthase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis. Isa MA, et al. J Mol Model, 2018 May 11. PMID 29752576
  2. Functional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purification. de Mendonça JD, et al. J Bacteriol, 2007 Sep. PMID 17586643, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis.
    Title: In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis.
  2. study presents the cloning, purification, and genetic complementation of the aroB gene
    Title: Functional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purification.
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Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
3-dehydroquinate synthase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2861588..2862676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217054.1 3-dehydroquinate synthase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217054.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654ZWS4
    Conserved Domains (1) summary
    PRK00002
    Location:8 → 361
    aroB; 3-dehydroquinate synthase; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WPX9.1

Gene LinkOut

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