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argF ornithine carbamoyltransferase ArgF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944844, updated on 2-May-2024

Summary

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Gene symbol
argF
Gene description
ornithine carbamoyltransferase ArgF
Primary source
ASAP:ABE-0000939
Locus tag
b0273
See related
ECOCYC:EG10067
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0274
Summary
argI and argF have same enzyme activity. [More information is available at EcoGene: EG10067]. In the test tube, not in the cell, a family of four isoenzymes forms by assortment of two closely similar polypeptides, the chain F-monomer and chain I-monomer, to give active trimers FFF, FFI, FII, and III. [More information is available at EcoCyc: EG10067].
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Genomic context

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Sequence:
NC_000913.3 (289301..290305, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative xylosidase/arabinosidase Neighboring gene DNA-binding transcriptional repressor XynR Neighboring gene putative translational regulatory protein ArgL Neighboring gene protein YkgS Neighboring gene IS1 family protein InsB Neighboring gene IS1 family protein InsA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Strengthened arm-dimerization domain interactions in AraC. Wu M, et al. J Biol Chem, 2001 Jan 26. PMID 11069917
  2. Nucleotide sequence of the argF regulatory region of Escherichia coli K-12. Moore SK, et al. Gene, 1981 Dec. PMID 6282686
  3. Characterization of P1argF derivatives from Escherichia coli K12 transduction. I. IS1 elements flank the argF gene segment. York MK, et al. Mol Gen Genet, 1981. PMID 6268940
  4. Mapping of IS1 elements flanking the argF gene region on the Escherichia coli K-12 chromosome. Hu M, et al. Mol Gen Genet, 1981. PMID 6268939
  5. Immunological and structural relatedness of catabolic ornithine carbamoyltransferases and the anabolic enzymes of enterobacteria. Falmagne P, et al. J Bacteriol, 1985 Feb. PMID 3968036, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Immunological and structural relatedness of catabolic ornithine carbamoyltransferases and the anabolic enzymes of enterobacteria.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ornithine carbamoyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ornithine carbamoyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ornithine carbamoyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in arginine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in arginine biosynthetic process via ornithine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in arginine biosynthetic process via ornithine NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in citrulline biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in citrulline biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in ornithine metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ornithine carbamoyltransferase ArgF
NP_414807.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    289301..290305 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414807.1 ornithine carbamoyltransferase ArgF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414807.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N8NMF6, A0A8T6A4I6
    Conserved Domains (1) summary
    PRK03515
    Location:1 → 332
    PRK03515; ornithine carbamoyltransferase subunit I; Provisional
Nucleotide Protein
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