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fabZ 3-hydroxy-acyl-[acyl-carrier-protein] dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944888, updated on 3-Dec-2024

Summary

Official Symbol
fabZ
Official Full Name
3-hydroxy-acyl-[acyl-carrier-protein] dehydratase
Primary source
ECOCYC:EG11284
Locus tag
b0180
See related
ASAP:ABE-0000613
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0179; sabA1; sefA; sfhC21; yaeA
Summary
Binds TrxA (Kumar, 2004). [More information is available at EcoGene: EG11284]. Certain mutations in fabZ have been found as suppressor mutations; its sabA1 allele changes the suppression of the OmpF315 phenotype by asmB1, and increased fabZ expression suppresses OmpF315 itself . [More information is available at EcoCyc: EG11284].
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Genomic context

Sequence:
NC_000913.3 (202101..202556)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic chaperone Skp Neighboring gene UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase Neighboring gene acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Neighboring gene lipid A disaccharide synthase Neighboring gene RNase HII

Interactions

General gene information

Gene Ontology Provided by EcoCyc

Component Evidence Code Pubs
located_in cytoplasm  
located_in membrane  

General protein information

Preferred Names
3-hydroxy-acyl-[acyl-carrier-protein] dehydratase
NP_414722.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    202101..202556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414722.1 3-hydroxy-acyl-[acyl-carrier-protein] dehydratase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414722.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376U2X3
    Conserved Domains (1) summary
    PRK00006
    Location:2150
    fabZ; 3-hydroxyacyl-ACP dehydratase FabZ
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