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dkgB methylglyoxal reductase DkgB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944901, updated on 11-Apr-2024

Summary

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Gene symbol
dkgB
Gene description
methylglyoxal reductase DkgB
Primary source
ASAP:ABE-0000692
Locus tag
b0207
See related
ECOCYC:EG11648
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0207; yafB
Summary
DkgB is a member of a new aldo-keto reductase (AKR) subfamily 3F . [More information is available at EcoCyc: EG11648].
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Genomic context

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Sequence:
NC_000913.3 (229167..229970)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene tRNA-Asp Neighboring gene DNA-binding transcriptional regulator YafC Neighboring gene endonuclease/exonuclease/phosphatase domain-containing protein YafD Neighboring gene putative S-adenosylmethionine-dependent methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the yqhE and yafB genes encoding two 2, 5-diketo-D-gluconate reductases in Escherichia coli. Yum DY, et al. Appl Environ Microbiol, 1999 Aug. PMID 10427017, Free PMC Article
  2. Sequence of the distal tRNA1Asp gene and the transcription termination signal in the Escherichia coli ribosomal RNA operon rrnF(or G). Sekiya T, et al. Nucleic Acids Res, 1980 Sep 11. PMID 6255418, Free PMC Article
  3. Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies. Di Luccio E, et al. Biochem J, 2006 Nov 15. PMID 16813561, Free PMC Article
  4. Conversion of methylglyoxal to acetol by Escherichia coli aldo-keto reductases. Ko J, et al. J Bacteriol, 2005 Aug. PMID 16077126, Free PMC Article
  5. A new model for the anaerobic fermentation of glycerol in enteric bacteria: trunk and auxiliary pathways in Escherichia coli. Gonzalez R, et al. Metab Eng, 2008 Sep. PMID 18632294

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aldo-keto reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aldo-keto reductase (NADPH) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables aryl-alcohol dehydrogenase (NADP+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables methylglyoxal reductase (NADPH) (acetol producing) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylglyoxal reductase (NADPH) (acetol producing) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-ascorbic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in methylglyoxal catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within methylglyoxal catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in small molecule metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
methylglyoxal reductase DkgB
NP_414743.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    229167..229970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414743.1 methylglyoxal reductase DkgB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414743.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YBZ2
    Conserved Domains (1) summary
    PRK11172
    Location:1 → 267
    dkgB; 2,5-didehydrogluconate reductase DkgB
Nucleotide Protein
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