pepD peptidase D [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: pepD
Gene description: peptidase D
Primary source: ASAP:ABE-0000809
Locus tag: b0237
See related: ECOCYC:EG10695
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0238; pepH
Summary: CsgD regulon, repressed. [More information is available at EcoGene: EG10695]. Peptidase D is a dipeptidase capable of breaking down a number of dipeptides with unblocked N termini, including cysteinylglycine . [More information is available at EcoCyc: EG10695].
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NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

N-terminus verified by Edman degradation on mature peptide
Title: Peptidase D of Escherichia coli K-12, a metallopeptidase of low substrate specificity.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables alanylglutamate dipeptidase activity	IEA Inferred from Electronic Annotation more info
enables dipeptidase activity	IEA Inferred from Electronic Annotation more info
enables dipeptidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables metallodipeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables metallodipeptidase activity	IDA Inferred from Direct Assay more info	PubMed
enables metallopeptidase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables zinc ion binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within peptide catabolic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_414772.1

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