U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

glxR tartronate semialdehyde reductase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945146, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
glxR
Gene description
tartronate semialdehyde reductase 2
Primary source
ASAP:ABE-0001759
Locus tag
b0509
See related
ECOCYC:G6278
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0502; glxB1; ybbQ
Summary
Tartronate semialdehyde reductase 2 (GlxR) catalyzes the reversible reactions of NAD+-dependent oxidation of D-glycerate and the NADH-dependent reduction of tartronate semialdehyde . [More information is available at EcoCyc: G6278].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (536586..537464)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene glyoxylate carboligase Neighboring gene hydroxypyruvate isomerase Neighboring gene putative allantoin transporter Neighboring gene allantoinase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. New developments in our understanding of the beta-hydroxyacid dehydrogenases. Njau RK, et al. Chem Biol Interact, 2001 Jan 30. PMID 11306094
  2. Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae. Njau RK, et al. J Biol Chem, 2000 Dec 8. PMID 10978349
  3. RutR is the uracil/thymine-sensing master regulator of a set of genes for synthesis and degradation of pyrimidines. Shimada T, et al. Mol Microbiol, 2007 Nov. PMID 17919280
  4. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071
  5. Biochemical evidence that Escherichia coli hyi (orf b0508, gip) gene encodes hydroxypyruvate isomerase. Ashiuchi M, et al. Biochim Biophys Acta, 1999 Nov 16. PMID 10561547

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-hydroxy-3-oxopropionate reductase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 2-hydroxy-3-oxopropionate reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within allantoin assimilation pathway IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in glycolate catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glyoxylate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in glyoxylate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in organic acid catabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tartronate semialdehyde reductase 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    536586..537464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415042.1 tartronate semialdehyde reductase 2 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415042.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AAR1, A0A5B9ALN3
    Conserved Domains (1) summary
    PRK15059
    Location:1 → 292
    PRK15059; 2-hydroxy-3-oxopropionate reductase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.