entD phosphopantetheinyl transferase EntD [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: entD
Gene description: phosphopantetheinyl transferase EntD
Primary source: ASAP:ABE-0002009
Locus tag: b0583
See related: ECOCYC:EG10262
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0575
Summary: AcpS is the founding member of a 4'-phosphopantetheinyl (P-pant) transferase protein family that includes Escherichia coli EntD, Escherichia coli o195 protein, and Bacillus subtilis Sfp; family members share two conserved motifs but relatively low sequence identity overall . [More information is available at EcoCyc: EG10262].
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NC_000913.3 Genomic Context describing neighboring genes

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Data suggest that EntD, a phosphopantetheinyl transferase, participates in the biosynthesis of the siderophore yersiniabactin.
Title: Interplay between siderophores and colibactin genotoxin biosynthetic pathways in Escherichia coli.
Escherichia coli highly expressed entD gene complements the pfaE deficiency in a pfa gene clone.
Title: The Escherichia coli highly expressed entD gene complements the pfaE deficiency in a pfa gene clone responsible for the biosynthesis of long-chain n-3 polyunsaturated fatty acids.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables holo-[acyl-carrier-protein] synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables holo-[acyl-carrier-protein] synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables holo-[acyl-carrier-protein] synthase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphotransferase activity, for other substituted phosphate groups	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in enterobactin biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within enterobactin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in siderophore metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of enterobactin synthetase complex	IDA Inferred from Direct Assay more info	PubMed
part_of enterobactin synthetase complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_415115.2

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The following sections contain reference sequences that belong to a specific genome build. Explain