U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mhpA 3-(3-hydroxyphenyl)propanoate hydroxylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945197, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
mhpA
Gene description
3-(3-hydroxyphenyl)propanoate hydroxylase
Primary source
ASAP:ABE-0001196
Locus tag
b0347
See related
ECOCYC:M010
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0344
Summary
visC, ubiH, ubiF and mhpA are paralogs. [More information is available at EcoGene: EG20273].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (368611..370275)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor LacI Neighboring gene DNA-binding transcriptional activator MhpR Neighboring gene 3-carboxyethylcatechol 2,3-dioxygenase Neighboring gene 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. MhpA Is a Hydroxylase Catalyzing the Initial Reaction of 3-(3-Hydroxyphenyl)Propionate Catabolism in Escherichia coli K-12. Xu Y, et al. Appl Environ Microbiol, 2020 Feb 3. PMID 31811039, Free PMC Article
  2. Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli. Torres B, et al. J Biol Chem, 2003 Jul 25. PMID 12748194
  3. Overproduction, purification and properties of 2,3-dihydroxyphenylpropionate 1,2-dioxygenase from Escherichia coli. Bugg TD. Biochim Biophys Acta, 1993 Oct 6. PMID 8399388
  4. Catabolism of phenylpropionic acid and its 3-hydroxy derivative by Escherichia coli. Burlingame R, et al. J Bacteriol, 1983 Jul. PMID 6345502, Free PMC Article
  5. Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation. Burlingame RP, et al. J Bacteriol, 1986 Oct. PMID 3531186, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3-(3-hydroxyphenyl)propionate hydroxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-(3-hydroxyphenyl)propionate hydroxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 3-(3-hydroxyphenyl)propionate hydroxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables FAD binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 3-(3-hydroxy)phenylpropionate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in 3-(3-hydroxy)phenylpropionate catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within 3-(3-hydroxy)phenylpropionate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in 3-phenylpropionate catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic compound catabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
3-(3-hydroxyphenyl)propanoate hydroxylase
NP_414881.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    368611..370275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414881.1 3-(3-hydroxyphenyl)propanoate hydroxylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414881.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N3HYP5
    Conserved Domains (1) summary
    PRK06183
    Location:1 → 544
    mhpA; bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.