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fepC ferric enterobactin ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945201, updated on 4-Apr-2024

Summary

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Gene symbol
fepC
Gene description
ferric enterobactin ABC transporter ATP binding subunit
Primary source
ASAP:ABE-0002025
Locus tag
b0588
See related
ECOCYC:EG10295
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0581
Summary
FepBCDG are components of a ferric enterobactin transport complex that is a member of the ATP-binding cassette (ABC) family of transporters. [More information is available at EcoCyc: EG10295].
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Genomic context

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Sequence:
NC_000913.3 (619384..620199, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ferric enterobactin esterase Neighboring gene enterobactin biosynthesis protein YbdZ Neighboring gene apo-serine activating enzyme Neighboring gene polysaccharide co-polymerase family protein FepE Neighboring gene ferric enterobactin ABC transporter membrane subunit FepG Neighboring gene ferric enterobactin ABC transporter membrane subunit FebD Neighboring gene enterobactin exporter EntS

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Escherichia coli K-12 envelope proteins specifically required for ferrienterobactin uptake. Pierce JR, et al. J Bacteriol, 1986 Jun. PMID 3011753, Free PMC Article
  2. Binding of ferric enterobactin by the Escherichia coli periplasmic protein FepB. Sprencel C, et al. J Bacteriol, 2000 Oct. PMID 10986237, Free PMC Article
  3. Escherichia coli periplasmic protein FepB binds ferrienterobactin. Stephens DL, et al. Microbiology (Reading), 1995 Jul. PMID 7551033
  4. Fur-DNA interactions at the bidirectional fepDGC-entS promoter region in Escherichia coli. Lavrrar JL, et al. J Mol Biol, 2002 Oct 4. PMID 12367523
  5. Mutations in the Escherichia coli receptor FepA reveal residues involved in ligand binding and transport. Barnard TJ, et al. Mol Microbiol, 2001 Aug. PMID 11532122

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ferric-enterobactin transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ferric-enterobactin import into cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in iron import into cell NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ferric enterobactin ABC transporter ATP binding subunit
NP_415120.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    619384..620199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415120.1 ferric enterobactin ABC transporter ATP binding subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415120.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7A2XXE8, A0A8S7EIJ9
    Conserved Domains (1) summary
    PRK10253
    Location:1 → 265
    PRK10253; iron-enterobactin ABC transporter ATP-binding protein
Nucleotide Protein
Heading Accession and Version

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