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pnuC nicotinamide riboside transporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945350, updated on 4-Feb-2024

Summary

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Gene symbol
pnuC
Gene description
nicotinamide riboside transporter
Primary source
ASAP:ABE-0002547
Locus tag
b0751
See related
ECOCYC:EG11700
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0740
Summary
The pnuC gene encodes a component of the Nicotinamide Mononucleotide (NMN) transport system. [More information is available at EcoCyc: EG11700].
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Genomic context

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Sequence:
NC_000913.3 (783166..783885)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene quinolinate synthase Neighboring gene Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter Neighboring gene PF13985 family protein YbgS Neighboring gene 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Assimilation of nicotinamide mononucleotide requires periplasmic AphA phosphatase in Salmonella enterica. Grose JH, et al. J Bacteriol, 2005 Jul. PMID 15968063, Free PMC Article
  2. Regulation of NAD metabolism in Salmonella typhimurium: genetic analysis and cloning of the nadR repressor locus. Foster JW, et al. Mol Gen Genet, 1987 Jun. PMID 3039308
  3. Pyridine nucleotide cycle of Salmonella typhimurium: in vitro demonstration of nicotinamide mononucleotide deamidase and characterization of pnuA mutants defective in nicotinamide mononucleotide transport. Kinney DM, et al. J Bacteriol, 1979 Nov. PMID 387742, Free PMC Article
  4. PnuC and the utilization of the nicotinamide riboside analog 3-aminopyridine in Haemophilus influenzae. Sauer E, et al. Antimicrob Agents Chemother, 2004 Dec. PMID 15561822, Free PMC Article
  5. Molecular biology of pyridine nucleotide biosynthesis in Escherichia coli. Cloning and characterization of quinolinate synthesis genes nadA and nadB. Flachmann R, et al. Eur J Biochem, 1988 Aug 1. PMID 2841129

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables nicotinamide riboside transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nicotinamide riboside transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within nicotinamide riboside transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nicotinamide riboside transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
nicotinamide riboside transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    783166..783885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415272.1 nicotinamide riboside transporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415272.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6AWY4
    Conserved Domains (1) summary
    PRK15397
    Location:1 → 239
    PRK15397; nicotinamide riboside transporter PnuC; Provisional
Nucleotide Protein
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