U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mngB alpha-mannosidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945359, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
mngB
Gene description
alpha-mannosidase
Primary source
ASAP:ABE-0002495
Locus tag
b0732
See related
ECOCYC:EG13236
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0720; ybgG
Summary
AFMB Structural Genomics target Number 109 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG13236]. The mngB gene encodes an alpha-mannosidase responsible for the conversion of 2-O-(6-phospho--mannosyl)-D-glycerate to mannose-6-phosphate and glycerate in the 2-O--Mannosyl-D-glycerate (MG) degradation pathway. [More information is available at EcoCyc: EG13236].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (767978..770611)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor MngR Neighboring gene 2-O-alpha-mannosyl-D-glycerate specific PTS enzyme II Neighboring gene cytochrome bd-I subunit 1 Neighboring gene cytochrome bd-I subunit 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Isolation and characterization of the heat-responsive genes in Escherichia coli. Utsumi R, et al. Biosci Biotechnol Biochem, 1996 Feb. PMID 9063979
  2. Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor. Sampaio MM, et al. J Biol Chem, 2004 Feb 13. PMID 14645248
  3. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
  4. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503
  5. Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Riley M, et al. Nucleic Acids Res, 2006. PMID 16397293, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha-mannosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-mannosidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
  
enables alpha-mannosidase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in mannose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in oligosaccharide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
alpha-mannosidase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    767978..770611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415260.1 alpha-mannosidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415260.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6M9WXW4
    Conserved Domains (1) summary
    PRK09819
    Location:2 → 875
    PRK09819; mannosylglycerate hydrolase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.