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bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945376, updated on 11-Apr-2024

Summary

Gene symbol
bioA
Gene description
adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Primary source
ASAP:ABE-0002635
Locus tag
b0774
See related
ECOCYC:EG10117
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0763
Summary
bioA encodes the 7,8-diaminopelargonic acid synthase enzyme in the biotin biosynthesis pathway. [More information is available at EcoCyc: EG10117].
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Genomic context

Sequence:
NC_000913.3 (807968..809257, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene outer membrane lipoprotein YbhC Neighboring gene putative kinase inhibitor Neighboring gene biotin synthase Neighboring gene 8-amino-7-oxononanoate synthase Neighboring gene malonyl-acyl carrier protein methyltransferase Neighboring gene dethiobiotin synthetase

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables adenosylmethionine-8-amino-7-oxononanoate transaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables adenosylmethionine-8-amino-7-oxononanoate transaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables adenosylmethionine-8-amino-7-oxononanoate transaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biotin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in biotin biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in biotin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in biotin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adenosylmethionine-8-amino-7-oxononanoate aminotransferase
NP_415295.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    807968..809257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415295.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415295.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7L5V2R5, A0A8S7CT89
    Conserved Domains (1) summary
    PRK07986
    Location:1428
    PRK07986; adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated