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pck phosphoenolpyruvate carboxykinase (ATP) [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945667, updated on 4-Apr-2024

Summary

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Gene symbol
pck
Gene description
phosphoenolpyruvate carboxykinase (ATP)
Primary source
ASAP:ABE-0011106
Locus tag
b3403
See related
ECOCYC:EG10688
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3390; pckA
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Genomic context

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Sequence:
NC_000913.3 (3532818..3534440)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene molecular chaperone Hsp33 Neighboring gene putative transport protein YhgE Neighboring gene sensor histidine kinase EnvZ Neighboring gene DNA-binding transcriptional dual regulator OmpR Neighboring gene transcription elongation factor GreB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Involvement of cAMP-CRP in transcription activation and repression of the pck gene encoding PEP carboxykinase, the key enzyme of gluconeogenesis. Nakano M, et al. FEMS Microbiol Lett, 2014 Jun. PMID 24814025
  2. How does an enzyme recognize CO2? Cotelesage JJ, et al. Int J Biochem Cell Biol, 2007. PMID 17475535
  3. Structure/function studies of phosphoryl transfer by phosphoenolpyruvate carboxykinase. Delbaere LT, et al. Biochim Biophys Acta, 2004 Mar 11. PMID 15023367
  4. Analysis of Escherichia coli anaplerotic metabolism and its regulation mechanisms from the metabolic responses to altered dilution rates and phosphoenolpyruvate carboxykinase knockout. Yang C, et al. Biotechnol Bioeng, 2003 Oct 20. PMID 12966569
  5. Mechanisms of activation of phosphoenolpyruvate carboxykinase from Escherichia coli by Ca2+ and of desensitization by trypsin. Sudom A, et al. J Bacteriol, 2003 Jul. PMID 12837799, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. cAMP-CRP associated at downstream CRP box-2 plays as a repressor for pck transcription only in the presence of high levels of cAMP-CRP
    Title: Involvement of cAMP-CRP in transcription activation and repression of the pck gene encoding PEP carboxykinase, the key enzyme of gluconeogenesis.
  2. N-terminus verified by Edman degradation on complete protein
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
phosphoenolpyruvate carboxykinase (ATP)
NP_417862.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3532818..3534440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417862.1 phosphoenolpyruvate carboxykinase (ATP) [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417862.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376LCK2, A0A7D7DKZ8, A0A8T3UJU3
    Conserved Domains (1) summary
    TIGR00224
    Location:3 → 540
    pckA; phosphoenolpyruvate carboxykinase (ATP)
Nucleotide Protein
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