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galU UTP--glucose-1-phosphate uridylyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945730, updated on 2-May-2024

Summary

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Gene symbol
galU
Gene description
UTP--glucose-1-phosphate uridylyltransferase
Primary source
ASAP:ABE-0004150
Locus tag
b1236
See related
ECOCYC:EG11319
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1231; ychD
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Genomic context

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Sequence:
NC_000913.3 (1291457..1292365)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative patatin-like phospholipase RssA Neighboring gene regulator of RpoS Neighboring gene DNA-binding transcriptional dual regulator H-NS Neighboring gene thymidine/deoxyuridine kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Active site geometry of glucose-1-phosphate uridylyltransferase. Thoden JB, et al. Protein Sci, 2007 Jul. PMID 17567737, Free PMC Article
  2. The molecular architecture of glucose-1-phosphate uridylyltransferase. Thoden JB, et al. Protein Sci, 2007 Mar. PMID 17322528, Free PMC Article
  3. Impact of heterologous expression of Escherichia coli UDP-glucose pyrophosphorylase on trehalose and glycogen synthesis in Corynebacterium glutamicum. Padilla L, et al. Appl Environ Microbiol, 2004 Jul. PMID 15240254, Free PMC Article
  4. General assay for sugar nucleotidyltransferases using electrospray ionization mass spectrometry. Zea CJ, et al. Anal Biochem, 2004 May 15. PMID 15113697
  5. THE SELECTIVITY OF BIOSYNTHESIS OF GLUCOSYL COMPOUNDS AS ILLUSTRATED BY AN E. COLI MUTANT DEFECTIVE IN UDPG SYNTHETASE. MAYER H, et al. Proc Natl Acad Sci U S A, 1965 Feb. PMID 14294082, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Single-mutations at the galactose-binding site of enzymes GalK, GalU, and LgtC enable the efficient synthesis of UDP-6-azido-6-deoxy-d-galactose and azido-functionalized Gb3 analogs.
    Title: Single-mutations at the galactose-binding site of enzymes GalK, GalU, and LgtC enable the efficient synthesis of UDP-6-azido-6-deoxy-d-galactose and azido-functionalized Gb3 analogs.
  2. N-terminus verified by Edman degradation on mature peptide
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables UTP:glucose-1-phosphate uridylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UTP:glucose-1-phosphate uridylyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in UDP-glucose metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within UDP-glucose metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within colanic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within galactose catabolic process via UDP-galactose IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within lipopolysaccharide core region biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within osmoregulated periplasmic glucan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
UTP--glucose-1-phosphate uridylyltransferase
NP_415752.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1291457..1292365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415752.1 UTP--glucose-1-phosphate uridylyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415752.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A447XYQ2
    Conserved Domains (1) summary
    PRK13389
    Location:1 → 302
    PRK13389; UTP--glucose-1-phosphate uridylyltransferase GalU
Nucleotide Protein
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