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agp glucose-1-phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945773, updated on 4-Apr-2024

Summary

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Gene symbol
agp
Gene description
glucose-1-phosphatase
Primary source
ASAP:ABE-0003388
Locus tag
b1002
See related
ECOCYC:EG10033
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0993
Summary
Requires DsbA for activity. [More information is available at EcoGene: EG10033]. Glucose-1-phosphatase, encoded by the agp gene, is a dimeric periplasmic enzyme that shows optimum glucose-1-phosphate hydrolysis activity at pH 4 . [More information is available at EcoCyc: EG10033].
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Genomic context

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Sequence:
NC_000913.3 (1065585..1066826)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene chaperone modulator CbpM Neighboring gene curved DNA-binding protein Neighboring gene uncharacterized protein YccE Neighboring gene PF13993 family protein YccJ Neighboring gene NAD(P)H:quinone oxidoreductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional insights revealed by the crystal structures of Escherichia coli glucose-1-phosphatase. Lee DC, et al. J Biol Chem, 2003 Aug 15. PMID 12782623
  2. Inositol phosphatase activity of the Escherichia coli agp-encoded acid glucose-1-phosphatase. Cottrill MA, et al. Can J Microbiol, 2002 Sep. PMID 12455612
  3. Purification, crystallization and preliminary X-ray analysis of the Escherichia coli glucose-1-phosphatase. Jia Z, et al. Acta Crystallogr D Biol Crystallogr, 2001 Feb. PMID 11173491
  4. Acid phosphatases of Escherichia coli: molecular cloning and analysis of agp, the structural gene for a periplasmic acid glucose phosphatase. Pradel E, et al. J Bacteriol, 1988 Oct. PMID 2844729, Free PMC Article
  5. Mapping of the Escherichia coli acid glucose-1-phosphatase gene agp and analysis of its expression in vivo by use of an agp-phoA protein fusion. Pradel E, et al. J Bacteriol, 1989 Jun. PMID 2542226, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3-phytase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucose-1-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucose-1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables sugar-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glucose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucose-1-phosphatase
NP_415522.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1065585..1066826
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415522.1 glucose-1-phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415522.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H9XMP1
    Conserved Domains (1) summary
    PRK10173
    Location:1 → 413
    PRK10173; glucose-1-phosphatase/inositol phosphatase; Provisional
Nucleotide Protein
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