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chaA Na(+)/K(+):H(+) antiporter ChaA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945790, updated on 11-Apr-2024

Summary

Gene symbol
chaA
Gene description
Na(+)/K(+):H(+) antiporter ChaA
Primary source
ASAP:ABE-0004082
Locus tag
b1216
See related
ECOCYC:EG11753
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1210
Summary
ChaA is a calcium ion: proton antiporter that is a member of the Calcium: [More information is available at EcoCyc: EG11753].
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Genomic context

Sequence:
NC_000913.3 (1270749..1271849, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene small toxic polypeptide LdrC Neighboring gene ncRNA Neighboring gene putative cation transport regulator ChaB Neighboring gene glutathione-specific gamma-glutamylcyclotransferase

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables potassium:proton antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables potassium:proton antiporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables sodium:proton antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sodium:proton antiporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to alkaline pH IDA
Inferred from Direct Assay
more info
PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
Na(+)/K(+):H(+) antiporter ChaA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1270749..1271849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415734.1 Na(+)/K(+):H(+) antiporter ChaA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415734.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6M9WWN6
    Conserved Domains (1) summary
    PRK10599
    Location:1366
    PRK10599; sodium-potassium/proton antiporter ChaA