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abgT p-aminobenzoyl glutamate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945912, updated on 4-Apr-2024

Summary

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Gene symbol
abgT
Gene description
p-aminobenzoyl glutamate:H(+) symporter
Primary source
ASAP:ABE-0004488
Locus tag
b1336
See related
ECOCYC:EG12853
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1332; ydaH
Summary
Artificial expression of abgT allows the uptake of p-aminobenzoyl-glutamate (Hussein, 1998; Carter, 2007). abgAB expression catalyzes the p-aminobenzoyl-glutamate assimilation to feed p-aminobenzoate auxotrophs (Carter, 2007). [More information is available at EcoGene: EG12853]. The AbgT protein is a possible p-aminobenzoyl-glutamate transporter. [More information is available at EcoCyc: EG12853].
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Genomic context

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Sequence:
NC_000913.3 (1400247..1401773, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator FNR Neighboring gene methylated-DNA--[protein]-cysteine S-methyltransferase Neighboring gene p-aminobenzoyl-glutamate hydrolase subunit B Neighboring gene p-aminobenzoyl-glutamate hydrolase subunit A Neighboring gene putative LysR-type DNA-binding transcriptional regulator AbgR

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli. Potter PM, et al. Nucleic Acids Res, 1987 Nov 25. PMID 2825131, Free PMC Article
  2. Escherichia coli abg genes enable uptake and cleavage of the folate catabolite p-aminobenzoyl-glutamate. Carter EL, et al. J Bacteriol, 2007 May. PMID 17307853, Free PMC Article
  3. Characterization of mutations that allow p-aminobenzoyl-glutamate utilization by Escherichia coli. Hussein MJ, et al. J Bacteriol, 1998 Dec. PMID 9829935, Free PMC Article
  4. Domain structure and pore loops in the 2-hydroxycarboxylate transporter family. Lolkema JS. J Mol Microbiol Biotechnol, 2006. PMID 17114896
  5. Sequence and hydropathy profile analysis of two classes of secondary transporters. Lolkema JS, et al. Mol Membr Biol, 2005 May-Jun. PMID 16096261

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables secondary active p-aminobenzoyl-glutamate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables secondary active p-aminobenzoyl-glutamate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables secondary active p-aminobenzoyl-glutamate transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables secondary active transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in p-aminobenzoyl-glutamate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in p-aminobenzoyl-glutamate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within p-aminobenzoyl-glutamate transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
p-aminobenzoyl glutamate:H(+) symporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1400247..1401773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415852.2 p-aminobenzoyl glutamate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415852.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EDK7, A0A8S7NQQ6
    Conserved Domains (1) summary
    PRK11339
    Location:1 → 508
    abgT; putative aminobenzoyl-glutamate transporter; Provisional
Nucleotide Protein
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