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tehB tellurite methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945979, updated on 2-May-2024

Summary

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Gene symbol
tehB
Gene description
tellurite methyltransferase
Primary source
ASAP:ABE-0004772
Locus tag
b1430
See related
ECOCYC:EG11884
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1423
Summary
The TehB protein in conjunction with TehA confers resistance to tellurite when expressed on a multicopy plasmid . [More information is available at EcoCyc: EG11884].
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Genomic context

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Sequence:
NC_000913.3 (1501562..1502155)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF465 domain-containing protein YdcH Neighboring gene ribosomal-protein-L12-serine N-acetyltransferase Neighboring gene putative acyltransferase YdcK Neighboring gene tellurite resistance protein Neighboring gene DUF3313 domain-containing lipoprotein YdcL Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli. Choudhury HG, et al. Biochem J, 2011 Apr 1. PMID 21244361
  2. The tellurite-resistance determinants tehAtehB and klaAklaBtelB have different biochemical requirements. Turner RJ, et al. Microbiology (Reading), 1995 Dec. PMID 8574407
  3. Escherichia coli TehB requires S-adenosylmethionine as a cofactor to mediate tellurite resistance. Liu M, et al. J Bacteriol, 2000 Nov. PMID 11053398, Free PMC Article
  4. The role of cysteine residues in tellurite resistance mediated by the TehAB determinant. Dyllick-Brenzinger M, et al. Biochem Biophys Res Commun, 2000 Oct 22. PMID 11032735
  5. Expression of Escherichia coli TehA gives resistance to antiseptics and disinfectants similar to that conferred by multidrug resistance efflux pumps. Turner RJ, et al. Antimicrob Agents Chemother, 1997 Feb. PMID 9021204, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
  
involved_in response to tellurium ion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to tellurium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to toxic substance IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
tellurite methyltransferase
NP_415947.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1501562..1502155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415947.1 tellurite methyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415947.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AK88, A0A7A3FC88
    Conserved Domains (1) summary
    PRK11207
    Location:1 → 196
    PRK11207; tellurite resistance methyltransferase TehB
Nucleotide Protein
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