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narW NarW, putative private chaperone for NarZ nitrate reductase subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946032, updated on 23-Nov-2023

Summary

Gene symbol
narW
Gene description
NarW, putative private chaperone for NarZ nitrate reductase subunit
Primary source
ASAP:ABE-0004892
Locus tag
b1466
See related
ECOCYC:EG10645
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
chlZ; ECK1460
Summary
NarW has two NarZ binding sites: one for Mo insertion and one to block membrane attachment via NarV until activation is complete. [More information is available at EcoGene: EG10645]. The polypeptide encoded by narW, the third gene in the narZYWV operon, is not part of the final nitrate reductase Z enzyme. [More information is available at EcoCyc: EG10645].
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Genomic context

Sequence:
NC_000913.3 (1536614..1537309, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene arylamine N-acetyltransferase Neighboring gene PF02567 family protein YddE Neighboring gene nitrate reductase Z subunit gamma Neighboring gene nitrate reductase Z subunit beta Neighboring gene nitrate reductase Z subunit alpha Neighboring gene nitrate/nitrite transporter NarU

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables metallochaperone activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chaperone-mediated protein complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in chaperone-mediated protein complex assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in nitrate assimilation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nitrate assimilation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NarW, putative private chaperone for NarZ nitrate reductase subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1536614..1537309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415983.1 NarW, putative private chaperone for NarZ nitrate reductase subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415983.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A775TKR0
    Conserved Domains (1) summary
    PRK15054
    Location:1231
    PRK15054; nitrate reductase molybdenum cofactor assembly chaperone