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fiu iron catecholate outer membrane transporter Fiu [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946246, updated on 23-Nov-2023

Summary

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Gene symbol
fiu
Gene description
iron catecholate outer membrane transporter Fiu
Primary source
ASAP:ABE-0002749
Locus tag
b0805
See related
ECOCYC:G6414
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0794; ybiL
Summary
Transport of catechol-substituted cephalosporins. [More information is available at EcoGene: EG13317]. B0805 is a putative outer membrane porin. [More information is available at EcoCyc: G6414].
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Genomic context

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Sequence:
NC_000913.3 (839249..841531, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene zinc finger domain-containing protein YbiI Neighboring gene PKHD-type hydroxylase YbiX Neighboring gene DUF1471 domain-containing protein McbA Neighboring gene 23S rRNA m(6)A1618 methyltransferase Neighboring gene moderate conductance mechanosensitive channel YbiO

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The structure of the bacterial iron-catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism. Grinter R, et al. J Biol Chem, 2019 Dec 20. PMID 31712312, Free PMC Article
  2. Cooperative uptake of microcin E492 by receptors FepA, Fiu, and Cir and inhibition by the siderophore enterochelin and its dimeric and trimeric hydrolysis products. Strahsburger E, et al. Antimicrob Agents Chemother, 2005 Jul. PMID 15980406, Free PMC Article
  3. Identification of an iron uptake system specific for coprogen and rhodotorulic acid in Escherichia coli K12. Hantke K. Mol Gen Genet, 1983. PMID 6353165
  4. Uptake of a catecholic cephalosporin by the iron transport system of Escherichia coli. Critchley IA, et al. J Antimicrob Chemother, 1991 Sep. PMID 1960119
  5. Changes in Escherichia coli outer membrane subproteome under environmental conditions inducing the viable but nonculturable state. Muela A, et al. FEMS Microbiol Ecol, 2008 Apr. PMID 18318713

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fiu is a bacterial iron-catecholate transporter that imports substrates via a two-step mechanism
    Title: The structure of the bacterial iron-catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables siderophore uptake transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables siderophore uptake transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables siderophore uptake transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables siderophore-iron transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular iron ion homeostasis NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microcin transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within siderophore transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within siderophore-dependent iron import into cell IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in siderophore-dependent iron import into cell IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within siderophore-dependent iron import into cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of transmembrane transporter complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
iron catecholate outer membrane transporter Fiu

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    839249..841531 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415326.1 iron catecholate outer membrane transporter Fiu [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415326.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A895P0X9
    Conserved Domains (1) summary
    PRK09840
    Location:1 → 760
    PRK09840; catecholate siderophore receptor Fiu; Provisional
Nucleotide Protein
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