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cpsB mannose-1-phosphate guanylyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946580, updated on 6-Oct-2023

Summary

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Gene symbol
cpsB
Gene description
mannose-1-phosphate guanylyltransferase
Primary source
ASAP:ABE-0006791
Locus tag
b2049
See related
ECOCYC:EG10161
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2043; manC; mni; rfbM
Summary
Mannose-1-phosphate guanylyltransferase is involved in the biosynthesis of the capsular polysaccharide colanic acid. [More information is available at EcoCyc: EG10161].
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Genomic context

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Sequence:
NC_000913.3 (2123084..2124520, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase Neighboring gene phosphomannomutase Neighboring gene colanic acid biosynthesis fucosyltransferase WcaI Neighboring gene GDP-mannose mannosyl hydrolase Neighboring gene GDP-L-fucose synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Depression of guanosine diphosphate-mannose pyrophosphorylase by mutations in two different regulator genes involved in capsular polysaccharide synthesis in Escherichia coli K-12. Lieberman MM, et al. J Bacteriol, 1970 Mar. PMID 4908790, Free PMC Article
  2. lon transcriptional regulation of genes necessary for capsular polysaccharide synthesis in Escherichia coli K-12. Trisler P, et al. J Bacteriol, 1984 Oct. PMID 6090411, Free PMC Article
  3. Regulation of capsular polysaccharide synthesis in Escherichia coli K12. Gottesman S, et al. Mol Microbiol, 1991 Jul. PMID 1943696
  4. Regulation of capsular polysaccharide synthesis in Escherichia coli K-12: characterization of three regulatory genes. Gottesman S, et al. J Bacteriol, 1985 Jun. PMID 3888955, Free PMC Article
  5. Capsule synthesis in Escherichia coli K-12 is regulated by proteolysis. Torres-Cabassa AS, et al. J Bacteriol, 1987 Mar. PMID 3029041, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General protein information

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Preferred Names
mannose-1-phosphate guanylyltransferase
NP_416553.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2123084..2124520 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416553.1 mannose-1-phosphate guanylyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416553.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A828NBL7
    Conserved Domains (1) summary
    PRK15460
    Location:1 → 478
    cpsB; mannose-1-phosphate guanyltransferase; Provisional
Nucleotide Protein
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