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gsk inosine/guanosine kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946584, updated on 4-Apr-2024

Summary

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Gene symbol
gsk
Gene description
inosine/guanosine kinase
Primary source
ASAP:ABE-0001655
Locus tag
b0477
See related
ECOCYC:EG11102
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0471
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Genomic context

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Sequence:
NC_000913.3 (500125..501429)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene adenylate kinase Neighboring gene ferrochelatase Neighboring gene acetylesterase Neighboring gene putative transporter YbaL Neighboring gene fosmidomycin efflux pump

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. End-product regulation and kinetic mechanism of guanosine-inosine kinase from Escherichia coli. Kawasaki H, et al. Biosci Biotechnol Biochem, 2000 May. PMID 10879466
  2. Role of guanosine kinase in the utilization of guanosine for nucleotide synthesis in Escherichia coli. Hove-Jensen B, et al. J Gen Microbiol, 1989 May. PMID 2559948
  3. gsk disruption leads to guanosine accumulation in Escherichia coli. Matsui H, et al. Biosci Biotechnol Biochem, 2001 May. PMID 11440147
  4. Location on the chromosome of Escherichia coli of genes governing purine metabolism. Adenosine deaminase (add), guanosine kinase (gsk) and hypoxanthine phosphoribosyltransferase (hpt). Jochimsen B, et al. Mol Gen Genet, 1975 Dec 30. PMID 765747
  5. Isolation and characterization of visible light-sensitive mutants of Escherichia coli K12. Miyamoto K, et al. J Mol Biol, 1991 Jun 5. PMID 2051480

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Cloning and characterization of the gsk gene encoding guanosine kinase of Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables guanosine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables guanosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables guanosine tetraphosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables inosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables inosine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables inosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in GMP salvage IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within GMP salvage IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in IMP salvage IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within IMP salvage IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in purine ribonucleoside salvage IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
inosine/guanosine kinase
NP_415010.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    500125..501429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415010.1 inosine/guanosine kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415010.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1V1IFM5, A0A1V1IFN1, A0A1V1IFN2, A0A1V1IGJ0, A0A1V1IGM6, A0A376DD56, A0A376RPI7
    Conserved Domains (1) summary
    PRK15074
    Location:1 → 434
    PRK15074; inosine/guanosine kinase; Provisional
Nucleotide Protein
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