hpt hypoxanthine phosphoribosyltransferase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: hpt
Gene description: hypoxanthine phosphoribosyltransferase
Primary source: ASAP:ABE-0000440
Locus tag: b0125
See related: ECOCYC:EG20098
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0124
Summary: Hypoxanthine phosphoribosyltransferase is a purine salvage enzyme whose primary activity is with hypoxanthine as the substrate . [More information is available at EcoCyc: EG20098].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables guanine phosphoribosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables guanine phosphoribosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables guanosine tetraphosphate binding	IDA Inferred from Direct Assay more info	PubMed
enables hypoxanthine phosphoribosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hypoxanthine phosphoribosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables hypoxanthine phosphoribosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables hypoxanthine phosphoribosyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables magnesium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables magnesium ion binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in GMP salvage	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within GMP salvage	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within GMP salvage	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in IMP salvage	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within IMP salvage	IDA Inferred from Direct Assay more info	PubMed
involved_in IMP salvage	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within IMP salvage	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in guanine salvage	IBA Inferred from Biological aspect of Ancestor more info
involved_in hypoxanthine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein homotetramerization	IDA Inferred from Direct Assay more info	PubMed
involved_in purine ribonucleoside salvage	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
part_of protein-containing complex	IDA Inferred from Direct Assay more info	PubMed

NP_414667.4

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