U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rihB pyrimidine-specific ribonucleoside hydrolase RihB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946646, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
rihB
Gene description
pyrimidine-specific ribonucleoside hydrolase RihB
Primary source
ASAP:ABE-0007156
Locus tag
b2162
See related
ECOCYC:EG12030
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2155; yeiK
Summary
The rihB gene encodes a ribonucleoside hydrolase that can utilize both cytidine and uridine, but shows a preference for cytidine . [More information is available at EcoCyc: EG12030].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (2254245..2255186, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative sugar kinase YeiI Neighboring gene putative nucleoside transporter Neighboring gene DNA-binding transcriptional activator YeiL Neighboring gene putative pseudouridine transporter

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Structural basis for substrate specificity in group I nucleoside hydrolases. Iovane E, et al. Biochemistry, 2008 Apr 15. PMID 18361502
  2. Accurate description of nitrogenous base flexibility in classical molecular dynamics simulations of nucleotides bound to proteins. Fornili A, et al. J Phys Chem B, 2007 Jun 14. PMID 17508739
  3. Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy. Giabbai B, et al. Structure, 2004 May. PMID 15130467
  4. Cloning, purification, crystallization and X-ray analysis of the Escherichia coli pyrimidine nucleoside hydrolase YeiK. Giabbai B, et al. Acta Crystallogr D Biol Crystallogr, 2004 Mar. PMID 14993681
  5. YeiL, the third member of the CRP-FNR family in Escherichia coli. Anjum MF, et al. Microbiology (Reading), 2000 Dec. PMID 11101674

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables calcium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, hydrolyzing N-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables purine nucleosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosylpyrimidine nucleosidase activity IEA
Inferred from Electronic Annotation
more info
  
enables uridine nucleosidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables uridine nucleosidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein homotetramerization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in purine nucleoside catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyrimidine nucleobase metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pyrimidine ribonucleoside catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pyrimidine ribonucleoside catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
pyrimidine-specific ribonucleoside hydrolase RihB
NP_416667.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2254245..2255186 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416667.1 pyrimidine-specific ribonucleoside hydrolase RihB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416667.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7J2R8, A0A8T6A6E1, W1WXD6
    Conserved Domains (1) summary
    PRK09955
    Location:1 → 313
    rihB; ribosylpyrimidine nucleosidase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.