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fruA fructose-specific PTS multiphosphoryl transfer protein FruA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946672, updated on 2-May-2024

Summary

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Gene symbol
fruA
Gene description
fructose-specific PTS multiphosphoryl transfer protein FruA
Primary source
ASAP:ABE-0007172
Locus tag
b2167
See related
ECOCYC:EG10336
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2160; ptsF
Summary
C-terminal domain, last 200 residues, is member of LysE superfamily. [More information is available at EcoGene: EG10336]. This subunit contains PTS Enzyme IIB', IIB and IIC domains. [More information is available at EcoCyc: EG10336].
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Genomic context

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Sequence:
NC_000913.3 (2259719..2261410, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative pseudouridine transporter Neighboring gene pseudouridine-5'-phosphate glycosidase Neighboring gene putative pseudouridine kinase Neighboring gene 1-phosphofructokinase Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A preliminary X-ray study of a refolded PTS EIIBfruc protein from Escherichia coli. Shin DH. Protein Pept Lett, 2008. PMID 18680461
  2. [Analysis of mutations affecting the expression of catabolite-sensitive operons in Escherichia coli K12 mutants defective in the HPr-component of the carbohydrate transport system]. Erlagaeva RS, et al. Mol Gen Mikrobiol Virusol, 1987 Feb. PMID 3553910
  3. [Determination of the direction of transcription of Escherichia coli K-12 structural genes of the fructose regulon in vivo]. Dobrynina OIu, et al. Genetika, 1995 Feb. PMID 7721070
  4. Function of the duplicated IIB domain and oligomeric structure of the fructose permease of Escherichia coli. Charbit A, et al. J Biol Chem, 1996 Apr 26. PMID 8626640
  5. Relationship between pseudo-HPr and the PEP: fructose phosphotransferase system in Salmonella typhimurium and Escherichia coli. Geerse RH, et al. Mol Gen Genet, 1986 Jun. PMID 3528748

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The synchrotron data were collected to 2.6 A from the crystal of a selenomethionine substitute PTS EIIB(fruc) protein.
    Title: A preliminary X-ray study of a refolded PTS EIIBfruc protein from Escherichia coli.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein-phosphocysteine-sugar phosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fructose import across plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of transmembrane transporter complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
fructose-specific PTS multiphosphoryl transfer protein FruA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2259719..2261410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416672.1 fructose-specific PTS multiphosphoryl transfer protein FruA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416672.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7D7DKN2, A0AA87HH81
    Conserved Domains (1) summary
    PRK10712
    Location:1 → 563
    PRK10712; PTS system fructose-specific transporter subunits IIBC; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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