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hisP lysine/arginine/ornithine ABC transporter/histidine ABC transporter, ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946789, updated on 4-Apr-2024

Summary

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Gene symbol
hisP
Gene description
lysine/arginine/ornithine ABC transporter/histidine ABC transporter, ATP binding subunit
Primary source
ASAP:ABE-0007610
Locus tag
b2306
See related
ECOCYC:EG10452
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2300
Summary
HisPMQJ is an ATP-dependent histidine transport system that is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10452].
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Genomic context

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Sequence:
NC_000913.3 (2423736..2424509, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene epimerase family protein YfcH Neighboring gene recombination-promoting nuclease RpnB Neighboring gene lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisM Neighboring gene lysine/arginine/ornithine ABC transporter/histidine ABC transporter, membrane subunit HisQ Neighboring gene histidine ABC transporter periplasmic binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Components of histidine transport: histidine-binding proteins and hisP protein. Ames GF, et al. Proc Natl Acad Sci U S A, 1970 Aug. PMID 4920090, Free PMC Article
  2. The nucleotide-binding site of HisP, a membrane protein of the histidine permease. Identification of amino acid residues photoaffinity labeled by 8-azido-ATP. Mimura CS, et al. J Biol Chem, 1990 Nov 15. PMID 2246240
  3. Sequence of the complete P protein gene and part of the M protein gene from the histidine transport operon of Escherichia coli compared to that of Salmonella typhimurium. Kraft R, et al. Nucleic Acids Res, 1987 Oct 26. PMID 3313284, Free PMC Article
  4. How are the ABC transporters energized? Nikaido H. Proc Natl Acad Sci U S A, 2002 Jul 23. PMID 12122215, Free PMC Article
  5. Characterization of transport through the periplasmic histidine permease using proteoliposomes reconstituted by dialysis. Liu CE, et al. J Biol Chem, 1997 Jan 10. PMID 8995374

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ABC-type amino acid transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables high-affinity L-histidine transmembrane transporter activity TAS
Traceable Author Statement
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-histidine import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within L-histidine import across plasma membrane TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within L-histidine transmembrane transport TAS
Traceable Author Statement
more info
 PubMed 
involved_in amino acid import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
lysine/arginine/ornithine ABC transporter/histidine ABC transporter, ATP binding subunit
NP_416809.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2423736..2424509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416809.1 lysine/arginine/ornithine ABC transporter/histidine ABC transporter, ATP binding subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416809.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6L7CA93
    Conserved Domains (1) summary
    PRK10619
    Location:1 → 257
    PRK10619; histidine ABC transporter ATP-binding protein HisP
Nucleotide Protein
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