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nanC N-acetylneuraminate outer membrane channel [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946843, updated on 2-May-2024

Summary

Gene symbol
nanC
Gene description
N-acetylneuraminate outer membrane channel
Primary source
ASAP:ABE-0014136
Locus tag
b4311
See related
ECOCYC:G7921
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4302; yjhA
Summary
In the absence of porins OmpF and OmpC (in an ompR mutant), NanC is required for the utilization of N-acetylneuraminic acid as a sole carbon source. [More information is available at EcoGene: EG12389]. Sequence similarity suggests that NanC is a member of the OmpG Porin (OmpG) family. nanC (yjhA) is the first gene in the yjhATS operon. [More information is available at EcoCyc: G7921].
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Genomic context

Sequence:
NC_000913.3 (4538785..4539501, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YthB Neighboring gene N-acetyl-9-O-acetylneuraminate esterase Neighboring gene N-acetylneuraminate mutarotase Neighboring gene Type 1 fimbriae regulatory protein FimB Neighboring gene regulator for fimA

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables oligosaccharide transporting porin activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables porin activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables porin activity IDA
Inferred from Direct Assay
more info
PubMed 
enables porin activity IEA
Inferred from Electronic Annotation
more info
 
enables porin activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables sialic acid transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in oligosaccharide transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within oligosaccharide transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
 
involved_in sialic acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cell outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
 
part_of pore complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-acetylneuraminate outer membrane channel

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4538785..4539501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418731.2 N-acetylneuraminate outer membrane channel [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418731.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6L6ZVF5
    Conserved Domains (1) summary
    cl11629
    Location:24236
    KdgM; Oligogalacturonate-specific porin protein (KdgM)