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yfeW penicillin binding protein 4B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946907, updated on 6-Oct-2023

Summary

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Gene symbol
yfeW
Gene description
penicillin binding protein 4B
Primary source
ASAP:ABE-0008012
Locus tag
b2430
See related
ECOCYC:G7265
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2425
Summary
A mutation in yfeW(pbp4a) does not affect growth on MurNAc (Jaeger, 2008). yfeW(pbp4a) is probably transcribed as part of the murQP-yfeW operon and from a promoter within murP (Jaeger, 2008). [More information is available at EcoGene: EG14164].
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Genomic context

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Sequence:
NC_000913.3 (2548102..2549406)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylmuramic acid 6-phosphate etherase Neighboring gene N-acetylmuramic acid-specific PTS enzyme IICB component/anhydro-N-acetylmuramic acid transporter Neighboring gene porphyrinogen peroxidase Neighboring gene DUF1131 domain-containing lipoprotein YfeY

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The DD-carboxypeptidase activity encoded by pbp4B is not essential for the cell growth of Escherichia coli. Vega D, et al. Arch Microbiol, 2006 Mar. PMID 16402224
  2. The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli. Jaeger T, et al. J Bacteriol, 2008 Oct. PMID 18723630, Free PMC Article
  3. MEROPS: the peptidase database. Rawlings ND, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381862, Free PMC Article
  4. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
  5. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables penicillin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type D-Ala-D-Ala carboxypeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables serine-type D-Ala-D-Ala carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
penicillin binding protein 4B

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2548102..2549406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416925.2 penicillin binding protein 4B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416925.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T6PYB3
    Conserved Domains (1) summary
    PRK03642
    Location:1 → 432
    PRK03642; putative periplasmic esterase; Provisional
Nucleotide Protein
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